package wfa type Result struct { Score int CIGAR string } type Penalty struct { M int X int O int E int } type Traceback byte const ( OpenIns Traceback = iota ExtdIns OpenDel ExtdDel Sub Ins Del End ) // bitpacked wavefront values with 1 valid bit, 3 traceback bits, and 28 bits for the diag distance // technically this restricts to solutions within 268 million score but that should be sufficient for most cases type WavefrontValue uint32 // TODO: add 64 bit packed value in case more than 268 million score is needed // PackWavefrontValue: packs a diag value and traceback into a WavefrontValue func PackWavefrontValue(value uint32, traceback Traceback) WavefrontValue { valueBM := value & 0x0FFF_FFFF tracebackBM := uint32(traceback&0x0000_0007) << 28 return WavefrontValue(0x8000_0000 | valueBM | tracebackBM) } // UnpackWavefrontValue: opens a WavefrontValue into a valid bool, diag value and traceback func UnpackWavefrontValue(wfv WavefrontValue) (bool, uint32, Traceback) { valueBM := uint32(wfv & 0x0FFF_FFFF) tracebackBM := uint8(wfv & 0x7000_0000 >> 28) validBM := wfv&0x8000_0000 != 0 return validBM, valueBM, Traceback(tracebackBM) } // Wavefront: stores a single wavefront, stores wavefront's lo value and hi is naturally lo + len(data) type Wavefront struct { // since wavefronts store diag distance, they should never be negative, and traceback data can be stored as uint8 data []WavefrontValue lo int } // NewWavefront: returns a new wavefront with size accomodating lo and hi (inclusive) func NewWavefront(lo int, hi int) *Wavefront { a := &Wavefront{} a.lo = lo size := a.TranslateIndex(hi) newData := make([]WavefrontValue, size+1) a.data = newData return a } // TranslateIndex: utility function for getting the data index given a diagonal func (a *Wavefront) TranslateIndex(diagonal int) int { return diagonal - a.lo } // Get: returns WavefrontValue for given diagonal func (a *Wavefront) Get(diagonal int) WavefrontValue { actualIdx := a.TranslateIndex(diagonal) if 0 <= actualIdx && actualIdx < len(a.data) { // idx is in the slice return a.data[actualIdx] } else { // idx is out of the slice return 0 } } // Set: the diagonal to a WavefrontValue func (a *Wavefront) Set(diagonal int, value WavefrontValue) { actualIdx := a.TranslateIndex(diagonal) /* in theory idx is always in bounds because the wavefront is preallocated if actualIdx < 0 || actualIdx >= len(a.data) { return } */ a.data[actualIdx] = value } // WavefrontComponent: each M/I/D wavefront matrix including the wavefront data, lo and hi type WavefrontComponent struct { lo *PositiveSlice[int] // lo for each wavefront hi *PositiveSlice[int] // hi for each wavefront W *PositiveSlice[*Wavefront] // wavefront diag distance and traceback for each wavefront } // NewWavefrontComponent: returns initialized WavefrontComponent func NewWavefrontComponent(preallocateSize int) *WavefrontComponent { // new wavefront component = { // lo = [0] // hi = [0] // W = [] // } w := &WavefrontComponent{ lo: &PositiveSlice[int]{ data: []int{0}, valid: []bool{true}, }, hi: &PositiveSlice[int]{ data: []int{0}, valid: []bool{true}, }, W: &PositiveSlice[*Wavefront]{ defaultValue: &Wavefront{ data: []WavefrontValue{0}, }, }, } w.lo.Preallocate(preallocateSize) w.hi.Preallocate(preallocateSize) w.W.Preallocate(preallocateSize) return w } // GetVal: get value for wavefront=score, diag=k => returns ok, value, traceback func (w *WavefrontComponent) GetVal(score int, k int) (bool, uint32, Traceback) { return UnpackWavefrontValue(w.W.Get(score).Get(k)) } // SetVal: set value, traceback for wavefront=score, diag=k func (w *WavefrontComponent) SetVal(score int, k int, val uint32, tb Traceback) { w.W.Get(score).Set(k, PackWavefrontValue(val, tb)) } // GetLoHi: get lo and hi for wavefront=score func (w *WavefrontComponent) GetLoHi(score int) (bool, int, int) { // if lo[score] and hi[score] are valid if w.lo.Valid(score) && w.hi.Valid(score) { // return lo[score] hi[score] return true, w.lo.Get(score), w.hi.Get(score) } else { return false, 0, 0 } } // SetLoHi: set lo and hi for wavefront=score func (w *WavefrontComponent) SetLoHi(score int, lo int, hi int) { // lo[score] = lo w.lo.Set(score, lo) // hi[score] = hi w.hi.Set(score, hi) // preemptively setup w.W b := NewWavefront(lo, hi) w.W.Set(score, b) }