Compare commits
6 Commits
Author | SHA1 | Date | |
---|---|---|---|
f1407fd045 | |||
ce635cc2b1 | |||
f5d2528e20 | |||
6f78825876 | |||
a878da42a3 | |||
bd720f06fb |
@ -5,7 +5,9 @@ Download `wfa.js` and `wfa.wasm`from [releases](https://git.tronnet.net/tronnet/
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```
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import wfa from "./wfa.js"
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await wfa("<path to wasm>")
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console.log(wfAlign(...))
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let result = wfAlign(...)
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operations = DecodeCIGAR(result.CIGAR)
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// ...
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```
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Where `<path to wasm>` is the path from the site root ie. `./scripts/wfa.wasm`. This will depend on your project structure.
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8
go.mod
8
go.mod
@ -3,13 +3,13 @@ module wfa
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go 1.23.2
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require (
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github.com/schollz/progressbar/v3 v3.17.0
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golang.org/x/exp v0.0.0-20241009180824-f66d83c29e7c
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github.com/schollz/progressbar/v3 v3.17.1
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golang.org/x/exp v0.0.0-20241108190413-2d47ceb2692f
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)
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require (
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github.com/mitchellh/colorstring v0.0.0-20190213212951-d06e56a500db // indirect
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github.com/rivo/uniseg v0.4.7 // indirect
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golang.org/x/sys v0.26.0 // indirect
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golang.org/x/term v0.25.0 // indirect
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golang.org/x/sys v0.27.0 // indirect
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golang.org/x/term v0.26.0 // indirect
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)
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49
main.go
49
main.go
@ -1,7 +1,6 @@
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package main
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import (
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"fmt"
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"syscall/js"
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wfa "wfa/pkg"
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)
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@ -15,32 +14,47 @@ func main() {
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func wfAlign(this js.Value, args []js.Value) interface{} {
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if len(args) != 4 {
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fmt.Println("invalid number of args, requires 4: s1, s2, penalties, doCIGAR")
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return nil
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resultMap := map[string]interface{}{
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"ok": false,
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"error": "invalid number of args, requires 4: s1, s2, penalties, doCIGAR",
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}
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return js.ValueOf(resultMap)
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}
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if args[0].Type() != js.TypeString {
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fmt.Println("s1 should be a string")
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return nil
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resultMap := map[string]interface{}{
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"ok": false,
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"error": "s1 should be a string",
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}
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return js.ValueOf(resultMap)
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}
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s1 := args[0].String()
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if args[1].Type() != js.TypeString {
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fmt.Println("s2 should be a string")
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return nil
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resultMap := map[string]interface{}{
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"ok": false,
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"error": "s2 should be a string",
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}
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return js.ValueOf(resultMap)
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}
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s2 := args[1].String()
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if args[2].Type() != js.TypeObject {
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fmt.Println("penalties should be a map with key values m, x, o, e")
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return nil
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resultMap := map[string]interface{}{
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"ok": false,
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"error": "penalties should be a map with key values m, x, o, e",
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}
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return js.ValueOf(resultMap)
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}
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if args[2].Get("m").IsUndefined() || args[2].Get("x").IsUndefined() || args[2].Get("o").IsUndefined() || args[2].Get("e").IsUndefined() {
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fmt.Println("penalties should be a map with key values m, x, o, e")
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return nil
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resultMap := map[string]interface{}{
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"ok": false,
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"error": "penalties should be a map with key values m, x, o, e",
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}
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return js.ValueOf(resultMap)
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}
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m := args[2].Get("m").Int()
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@ -56,8 +70,11 @@ func wfAlign(this js.Value, args []js.Value) interface{} {
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}
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if args[3].Type() != js.TypeBoolean {
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fmt.Println("doCIGAR should be a boolean")
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return nil
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resultMap := map[string]interface{}{
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"ok": false,
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"error": "doCIGAR should be a boolean",
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}
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return js.ValueOf(resultMap)
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}
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doCIGAR := args[3].Bool()
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@ -65,8 +82,10 @@ func wfAlign(this js.Value, args []js.Value) interface{} {
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// Call the actual func.
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result := wfa.WFAlign(s1, s2, penalties, doCIGAR)
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resultMap := map[string]interface{}{
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"ok": true,
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"score": result.Score,
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"CIGAR": result.CIGAR,
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"error": "",
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}
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return js.ValueOf(resultMap)
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@ -74,12 +93,12 @@ func wfAlign(this js.Value, args []js.Value) interface{} {
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func DecodeCIGAR(this js.Value, args []js.Value) interface{} {
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if len(args) != 1 {
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fmt.Println("invalid number of args, requires 1: CIGAR")
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println("invalid number of args, requires 1: CIGAR")
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return nil
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}
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if args[0].Type() != js.TypeString {
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fmt.Println("CIGAR should be a string")
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println("CIGAR should be a string")
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return nil
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}
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@ -41,15 +41,3 @@ func (a *PositiveSlice[T]) Set(idx int, value T) {
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a.data[actualIdx] = value
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a.valid[actualIdx] = true
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}
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func (a *PositiveSlice[T]) Preallocate(hi int) {
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size := hi
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// expand data array to actualIdx
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newData := make([]T, size+1)
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a.data = newData
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// expand valid array to actualIdx
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newValid := make([]bool, size+1)
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a.valid = newValid
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}
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16
pkg/debug.go
16
pkg/debug.go
@ -1,3 +1,5 @@
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//go:build debug
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package wfa
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import (
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@ -12,11 +14,13 @@ func (w *WavefrontComponent) String(score int) string {
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max_hi := math.MinInt
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for i := 0; i <= score; i++ {
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if w.lo.Valid(i) && w.lo.Get(i) < min_lo {
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min_lo = w.lo.Get(i)
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valid := w.W.Valid(i)
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lo, hi := UnpackWavefrontLoHi(w.W.Get(i).lohi)
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if valid && lo < min_lo {
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min_lo = lo
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}
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if w.hi.Valid(i) && w.hi.Get(i) > max_hi {
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max_hi = w.hi.Get(i)
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if valid && hi > max_hi {
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max_hi = hi
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}
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}
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@ -40,9 +44,7 @@ func (w *WavefrontComponent) String(score int) string {
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for i := 0; i <= score; i++ {
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s = s + "["
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lo := w.lo.Get(i)
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hi := w.hi.Get(i)
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// print out wavefront matrix
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lo, hi := UnpackWavefrontLoHi(w.W.Get(i).lohi)
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for k := min_lo; k <= max_hi; k++ {
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valid, val, _ := UnpackWavefrontValue(w.W.Get(i).Get(k))
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if valid {
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|
70
pkg/types.go
70
pkg/types.go
@ -25,39 +25,55 @@ const (
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End
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)
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// bitpacked wavefront lo/hi values with 32 bits each
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type WavefrontLoHi uint64
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func PackWavefrontLoHi(lo int, hi int) WavefrontLoHi {
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loBM := int64(int32(lo)) & 0x0000_0000_FFFF_FFFF
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hiBM := int64(int64(hi) << 32)
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return WavefrontLoHi(hiBM | loBM)
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}
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func UnpackWavefrontLoHi(lohi WavefrontLoHi) (int, int) {
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loBM := int(int32(lohi & 0x0000_0000_FFFF_FFFF))
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hiBM := int(int32(lohi & 0xFFFF_FFFF_0000_0000 >> 32))
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return loBM, hiBM
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}
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// bitpacked wavefront values with 1 valid bit, 3 traceback bits, and 28 bits for the diag distance
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// technically this restricts to solutions within 268 million score but that should be sufficient for most cases
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// technically this restricts to alignments with less than 268 million characters but that should be sufficient for most cases
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type WavefrontValue uint32
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// TODO: add 64 bit packed value in case more than 268 million score is needed
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// TODO: add 64 bit packed value in case more than 268 million characters are needed
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// PackWavefrontValue: packs a diag value and traceback into a WavefrontValue
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func PackWavefrontValue(value uint32, traceback Traceback) WavefrontValue {
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valueBM := value & 0x0FFF_FFFF
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validBM := uint32(0x8000_0000)
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tracebackBM := uint32(traceback&0x0000_0007) << 28
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return WavefrontValue(0x8000_0000 | valueBM | tracebackBM)
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valueBM := value & 0x0FFF_FFFF
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return WavefrontValue(validBM | tracebackBM | valueBM)
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}
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// UnpackWavefrontValue: opens a WavefrontValue into a valid bool, diag value and traceback
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func UnpackWavefrontValue(wfv WavefrontValue) (bool, uint32, Traceback) {
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valueBM := uint32(wfv & 0x0FFF_FFFF)
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tracebackBM := uint8(wfv & 0x7000_0000 >> 28)
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validBM := wfv&0x8000_0000 != 0
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tracebackBM := uint8(wfv & 0x7000_0000 >> 28)
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valueBM := uint32(wfv & 0x0FFF_FFFF)
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return validBM, valueBM, Traceback(tracebackBM)
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}
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// Wavefront: stores a single wavefront, stores wavefront's lo value and hi is naturally lo + len(data)
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type Wavefront struct { // since wavefronts store diag distance, they should never be negative, and traceback data can be stored as uint8
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data []WavefrontValue
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lo int
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lohi WavefrontLoHi
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}
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// NewWavefront: returns a new wavefront with size accomodating lo and hi (inclusive)
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func NewWavefront(lo int, hi int) *Wavefront {
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a := &Wavefront{}
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a.lo = lo
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size := a.TranslateIndex(hi)
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a.lohi = PackWavefrontLoHi(lo, hi)
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size := hi - lo
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newData := make([]WavefrontValue, size+1)
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a.data = newData
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@ -67,7 +83,8 @@ func NewWavefront(lo int, hi int) *Wavefront {
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// TranslateIndex: utility function for getting the data index given a diagonal
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func (a *Wavefront) TranslateIndex(diagonal int) int {
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return diagonal - a.lo
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lo := int(int32(a.lohi & 0x0000_0000_FFFF_FFFF))
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return diagonal - lo
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}
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// Get: returns WavefrontValue for given diagonal
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@ -95,27 +112,17 @@ func (a *Wavefront) Set(diagonal int, value WavefrontValue) {
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// WavefrontComponent: each M/I/D wavefront matrix including the wavefront data, lo and hi
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type WavefrontComponent struct {
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lo *PositiveSlice[int] // lo for each wavefront
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hi *PositiveSlice[int] // hi for each wavefront
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W *PositiveSlice[*Wavefront] // wavefront diag distance and traceback for each wavefront
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}
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// NewWavefrontComponent: returns initialized WavefrontComponent
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func NewWavefrontComponent(preallocateSize int) WavefrontComponent {
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func NewWavefrontComponent() *WavefrontComponent {
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// new wavefront component = {
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// lo = [0]
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// hi = [0]
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// W = []
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// }
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w := WavefrontComponent{
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lo: &PositiveSlice[int]{
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data: []int{0},
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valid: []bool{true},
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},
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hi: &PositiveSlice[int]{
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data: []int{0},
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valid: []bool{true},
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},
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w := &WavefrontComponent{
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W: &PositiveSlice[*Wavefront]{
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defaultValue: &Wavefront{
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data: []WavefrontValue{0},
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@ -123,10 +130,6 @@ func NewWavefrontComponent(preallocateSize int) WavefrontComponent {
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},
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}
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w.lo.Preallocate(preallocateSize)
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w.hi.Preallocate(preallocateSize)
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w.W.Preallocate(preallocateSize)
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||||
|
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return w
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}
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||||
|
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@ -142,23 +145,12 @@ func (w *WavefrontComponent) SetVal(score int, k int, val uint32, tb Traceback)
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|
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// GetLoHi: get lo and hi for wavefront=score
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func (w *WavefrontComponent) GetLoHi(score int) (bool, int, int) {
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// if lo[score] and hi[score] are valid
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if w.lo.Valid(score) && w.hi.Valid(score) {
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// return lo[score] hi[score]
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return true, w.lo.Get(score), w.hi.Get(score)
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} else {
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return false, 0, 0
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}
|
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lo, hi := UnpackWavefrontLoHi(w.W.Get(score).lohi)
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return w.W.Valid(score), lo, hi
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}
|
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|
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// SetLoHi: set lo and hi for wavefront=score
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func (w *WavefrontComponent) SetLoHi(score int, lo int, hi int) {
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// lo[score] = lo
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w.lo.Set(score, lo)
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// hi[score] = hi
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w.hi.Set(score, hi)
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|
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// preemptively setup w.W
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b := NewWavefront(lo, hi)
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w.W.Set(score, b)
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}
|
||||
|
@ -95,7 +95,7 @@ func SafeArgMin[T constraints.Integer](valids []bool, values []T) (bool, int) {
|
||||
}
|
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}
|
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|
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func NextLoHi(M WavefrontComponent, I WavefrontComponent, D WavefrontComponent, score int, penalties Penalty) (int, int) {
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func NextLoHi(M *WavefrontComponent, I *WavefrontComponent, D *WavefrontComponent, score int, penalties Penalty) (int, int) {
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x := penalties.X
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o := penalties.O
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e := penalties.E
|
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@ -125,7 +125,7 @@ func NextLoHi(M WavefrontComponent, I WavefrontComponent, D WavefrontComponent,
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return lo, hi
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}
|
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|
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func NextI(M WavefrontComponent, I WavefrontComponent, score int, k int, penalties Penalty) {
|
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func NextI(M *WavefrontComponent, I *WavefrontComponent, score int, k int, penalties Penalty) {
|
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o := penalties.O
|
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e := penalties.E
|
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|
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@ -139,7 +139,7 @@ func NextI(M WavefrontComponent, I WavefrontComponent, score int, k int, penalti
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}
|
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}
|
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|
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func NextD(M WavefrontComponent, D WavefrontComponent, score int, k int, penalties Penalty) {
|
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func NextD(M *WavefrontComponent, D *WavefrontComponent, score int, k int, penalties Penalty) {
|
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o := penalties.O
|
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e := penalties.E
|
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|
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@ -153,7 +153,7 @@ func NextD(M WavefrontComponent, D WavefrontComponent, score int, k int, penalti
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}
|
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}
|
||||
|
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func NextM(M WavefrontComponent, I WavefrontComponent, D WavefrontComponent, score int, k int, penalties Penalty) {
|
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func NextM(M *WavefrontComponent, I *WavefrontComponent, D *WavefrontComponent, score int, k int, penalties Penalty) {
|
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x := penalties.X
|
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|
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a_ok, a, _ := M.GetVal(score-x, k)
|
||||
|
13
pkg/wfa.go
13
pkg/wfa.go
@ -10,12 +10,11 @@ func WFAlign(s1 string, s2 string, penalties Penalty, doCIGAR bool) Result {
|
||||
A_k := m - n
|
||||
A_offset := uint32(m)
|
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score := 0
|
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estimatedScore := (max(n, m) * max(penalties.M, penalties.X, penalties.O, penalties.E)) / 4
|
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M := NewWavefrontComponent(estimatedScore)
|
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M := NewWavefrontComponent()
|
||||
M.SetLoHi(0, 0, 0)
|
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M.SetVal(0, 0, 0, End)
|
||||
I := NewWavefrontComponent(estimatedScore)
|
||||
D := NewWavefrontComponent(estimatedScore)
|
||||
I := NewWavefrontComponent()
|
||||
D := NewWavefrontComponent()
|
||||
|
||||
for {
|
||||
WFExtend(M, s1, n, s2, m, score)
|
||||
@ -38,7 +37,7 @@ func WFAlign(s1 string, s2 string, penalties Penalty, doCIGAR bool) Result {
|
||||
}
|
||||
}
|
||||
|
||||
func WFExtend(M WavefrontComponent, s1 string, n int, s2 string, m int, score int) {
|
||||
func WFExtend(M *WavefrontComponent, s1 string, n int, s2 string, m int, score int) {
|
||||
_, lo, hi := M.GetLoHi(score)
|
||||
for k := lo; k <= hi; k++ {
|
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// v = M[score][k] - k
|
||||
@ -60,7 +59,7 @@ func WFExtend(M WavefrontComponent, s1 string, n int, s2 string, m int, score in
|
||||
}
|
||||
}
|
||||
|
||||
func WFNext(M WavefrontComponent, I WavefrontComponent, D WavefrontComponent, score int, penalties Penalty) {
|
||||
func WFNext(M *WavefrontComponent, I *WavefrontComponent, D *WavefrontComponent, score int, penalties Penalty) {
|
||||
// get this score's lo, hi
|
||||
lo, hi := NextLoHi(M, I, D, score, penalties)
|
||||
|
||||
@ -71,7 +70,7 @@ func WFNext(M WavefrontComponent, I WavefrontComponent, D WavefrontComponent, sc
|
||||
}
|
||||
}
|
||||
|
||||
func WFBacktrace(M WavefrontComponent, I WavefrontComponent, D WavefrontComponent, score int, penalties Penalty, A_k int, A_offset uint32, s1 string, s2 string) string {
|
||||
func WFBacktrace(M *WavefrontComponent, I *WavefrontComponent, D *WavefrontComponent, score int, penalties Penalty, A_k int, A_offset uint32, s1 string, s2 string) string {
|
||||
x := penalties.X
|
||||
o := penalties.O
|
||||
e := penalties.E
|
||||
|
@ -12,6 +12,7 @@ import (
|
||||
wfa "wfa/pkg"
|
||||
|
||||
"github.com/schollz/progressbar/v3"
|
||||
"golang.org/x/exp/constraints"
|
||||
)
|
||||
|
||||
const testJsonPath = "tests.json"
|
||||
@ -29,14 +30,14 @@ type TestCase struct {
|
||||
Solutions string `json:"solutions"`
|
||||
}
|
||||
|
||||
func randRange(min, max int) uint32 {
|
||||
return uint32(rand.IntN(max-min) + min)
|
||||
func randRange[T constraints.Integer](min, max int) T {
|
||||
return T(rand.IntN(max-min) + min)
|
||||
}
|
||||
|
||||
func TestWavefrontPacking(t *testing.T) {
|
||||
for range 1000 {
|
||||
val := randRange(0, 1000)
|
||||
tb := wfa.Traceback(randRange(0, 7))
|
||||
val := randRange[uint32](0, 1000)
|
||||
tb := wfa.Traceback(randRange[uint32](0, 7))
|
||||
v := wfa.PackWavefrontValue(val, tb)
|
||||
|
||||
valid, gotVal, gotTB := wfa.UnpackWavefrontValue(v)
|
||||
@ -47,6 +48,20 @@ func TestWavefrontPacking(t *testing.T) {
|
||||
}
|
||||
}
|
||||
|
||||
func TestLoHiPacking(t *testing.T) {
|
||||
for range 1000 {
|
||||
lo := randRange[int](-1000, 1000)
|
||||
hi := randRange[int](-1000, 1000)
|
||||
v := wfa.PackWavefrontLoHi(lo, hi)
|
||||
|
||||
gotLo, gotHi := wfa.UnpackWavefrontLoHi(v)
|
||||
|
||||
if gotLo != lo || gotHi != hi {
|
||||
t.Errorf(`test WavefrontPack/Unpack, lo: %d, hi: %d, packedval: %x, gotlo: %d, gothi: %d`, lo, hi, v, gotLo, gotHi)
|
||||
}
|
||||
}
|
||||
}
|
||||
|
||||
func GetScoreFromCIGAR(CIGAR string, penalties wfa.Penalty) int {
|
||||
unpackedCIGAR := wfa.RunLengthDecode(CIGAR)
|
||||
previousOp := '~'
|
||||
|
Loading…
Reference in New Issue
Block a user